VHL ELISA Kit for Dog(Canis familiaris) | EIAab.comVHL ELISA Kit for Dog(Canis familiaris)

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Index > Protein center > VHL(Gene name) > Dog

VHL (Gene name),

Von Hippel-Lindau disease tumor suppressor (Protein name ), VHL_CANFA from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

VHL;

Protein name:

Von Hippel-Lindau disease tumor suppressor;

Alternative:

pVHL;

Organism:

Dog (Canis familiarisCanis lupus familiaris).

General Annotation

Sub Unit:

Part of a complex with Elongin BC complex and hydroxylated HIF1A. Interacts with CUL2. Part of multisubunit CBC(VHL) E3 ubiquitin ligase complexes with Elongin BC complex, CUL2 or CUL5 and RBX1. Interacts with HIF1AN. Part of a complex with HIF1A, HIF1AN and HDAC1 or HDAC2 or HDAC3. The C-terminus interacts with VBP1. Interacts with RNF139 and UBP33. Interacts with PHF17.

Function:

Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases.

Subcellular Location:

Cytoplasm Membrane Peripheral membrane protein Nucleus

Protein Attributes:

Sequence length:

219

Sequence:

50:

100:

150:

200:

219:

LAQEHIENQR | MEGETEDFN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF01847

SMR:

Q5Q9Z2

UniGene:

Cfa.16229

KEGG:

cfa:494000

String:

Q5Q9Z2

STRING:

9615.ENSCAFP00000007687

Uniprot:

Q5Q9Z2

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ELISA Kit for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

E1894h

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96T

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ELISA Kit for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

E1894r

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Packing:

96T

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ELISA Kit for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

E1894m

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MSDS:

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Packing:

96T

ELISA Kit for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

E1894d

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Packing:

96T

CLIA Kit for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

U1894d

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Packing:

96T

CLIA Kit for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

U1894h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

U1894m

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MSDS:

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Packing:

96T

CLIA Kit for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

U1894r

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

P1894Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

P1894Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Dog Von Hippel-Lindau disease tumor suppressor

Cat.:

P1894Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Dog Von Hippel-Lindau disease tumor suppressor

Protein for Dog Von Hippel-Lindau disease tumor suppressor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"cDNA sequence of canine von Hippel-Lindau disease tumor suppressor gene."
Kobayashi N. , Sato T. , Shibuya H. , Suzuki K.
Submitted (2004-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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